- Original Article
- Endocrinology
- Final height of Korean patients with early treated congenital hypothyroidism
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Jiyun Lee, Jeongho Lee, Dong Hwan Lee
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Clin Exp Pediatr. 2018;61(7):221-225. Published online July 15, 2018
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Purpose: Congenital hypothyroidism (CH) is the most common endocrine disorder in children. Thyroid hormone deprivation results not only in mental retardation but also growth retardation. This study investigates the final height (FH) in Korean patients with CH detected by newborn screening and examines factors that may affect the FH.
Methods: The medical records of Korean CH patients (n=45) were reviewed. The... |
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- Characteristics of thyroid nodules in infant with congenital hypothyroidism
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Seo Young Youn, Jeong Ho Lee, Yun-Woo Chang, Dong Hwan Lee
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Clin Exp Pediatr. 2014;57(2):85-90. Published online February 24, 2014
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Purpose This study aimed to assess the characteristics of thyroid nodules among infants diagnosed with congenital hypothyroidism. MethodsA retrospective study of 660 infants (374 males, 286 females) diagnosed with congenital hypothyroidism was carried out at the Pediatric Endocrine Clinic in Soonchunhyang University Hospital, Korea, between May 2003 and February 2013. The average age at diagnosis was 1.16±1.68 months. ResultsOf the 28 patients (4.2%)... |
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- Spectrum of patients with hypermethioninemia based on neonatal screening tests over 14 years
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Se Jung Oh, Yong Hee Hong, Yong Wha Lee, Dong Hwan Lee
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Clin Exp Pediatr. 2010;53(3):329-334. Published online March 15, 2010
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Purpose : The neonatal screening test for homocystinuria primarily measures methionine by using a dried blood specimen. We investigated the incidence and clinical manifestations of homocystinuria, isolated hypermethioninemia, and transient hypermethioninemia among patients with hypermethioninemia on a neonatal screening test.
Methods : We performed a retrospective study of 58 patients transferred to Shoonchunhyang Hospital because of hypermethioninemia on a neonatal... |
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- Case Report
- Two cases of Fabry disease identified in brothers
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Ji Eun Cho, Yong Hee Hong, Yang Gyun Lee, Han Wook Yoo, Dong Hwan Lee
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Clin Exp Pediatr. 2010;53(2):235-238. Published online February 15, 2010
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Fabry disease is a rare, X-linked inborn error of glycosphingolipid catabolism caused by a mutation in the gene encoding the α-galactosidase A (GLA) enzyme. We report two cases of Fabry disease in a 12-year-old boy who had acroparesthesia and in his elder brother with milder symptoms who were diagnosed by GLA activity assays and the presence of the GLA gene... |
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- Review Article
- The prevalence of pediatric endocrine and metabolic diseases in Korea
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Dong Hwan Lee
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Clin Exp Pediatr. 2008;51(6):559-563. Published online June 15, 2008
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The government neonatal screening program has a 17-years history. Therefore, it can now provide information on the prevalence of endocrine and metabolic diseases which included in neonatal screening. Knowledge of the prevalence of metabolic diseases is very important with these results, the most effective screening methods can be determined and diseases can be identified that should be added to neonatal... |
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- Case Report
- Clinical improvement in a case of atypical infantile onset Pompe disease with enzyme replacement therapy
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You Hoon Jeon, Baik-Lin Eun, Chang Sung Son, Dong Hwan Lee
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Clin Exp Pediatr. 2007;50(2):213-217. Published online February 15, 2007
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Pompe disease is a genetic disorder caused by a deficiency of acid α-glucosidase (GAA). Infantile onset Pompe disease is uniformly lethal. Affected infants generally present in the first few months of life with hypotonia, generalized muscle weakness, and a hypertrophic cardiomyopathy, which is rapidly followed by death, usually by the age of one. The late-onset form is characterized less severe... |
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- Original Article
- Evaluation of diagnostic methods in children with nonpalpable undescended testis
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Noh Sung Seok, Hong Jin Suh, Dong Hwan Lee
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Clin Exp Pediatr. 2006;49(7):732-736. Published online July 15, 2006
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Purpose : Numerous methods exist for diagnosing nonpalpable testis in treatment of cryptochidism. However, there is no clinically established data for the rational diagnostic tool of nonpalpable testis in terms of expenses. We tried to establish a current conventional diagnostic course of nonpalpable testis. We then evaluated the efficacy of ultrasonography, physical examination under general anesthesia and laparoscopy for diagnosing... |
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- Review Article
- Newborn screening of inherited metabolic disease in Korea
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Dong Hwan Lee
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Clin Exp Pediatr. 2006;49(11):1125-1139. Published online November 15, 2006
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In 1991, the Ministry of Health & Social affairs adopted a nationwide service program for neonatal screening of phenylketonuria, galactosemia, maple syrup urine disease, homocystinuria, histidinemia & congenital hypothyroidism for newborns delivered from low class pregnant women registered in health centers. Government decreased the test items from six to two, PKU & congenital hypothyroidism to increase test numbers with same... |
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- Original Article
- Carotid Intima-Media Thickness Measurement in Obese Children
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Kyung Ok Park, Suk Ju Choi, Hee Hyun Yeom, Sochung Chung, Jeong Jin Yu, Youngshin Park, Dong Hwan Lee
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Clin Exp Pediatr. 2005;48(9):935-938. Published online September 15, 2005
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Purpose : The aim of the present study was to ascertain whether the increase of carotid intima- media thickeness(cIMT) as one of premature pathologic changes of atherosclerosis, was present in obese children compared to normal weight children.
Methods : The obese group consisted of 21 obese/overweight(body mass index(BMI) above 85 percentile of age, sex standards) children and the control group of... |
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- A Cost-benefit Analysis on Neonatal Screening of Phenylketonuria and Congenital Hypothyroidism in Korea
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Hoe Cheol Yoon, Nyeon Cheon Kim, Dong Hwan Lee
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Clin Exp Pediatr. 2005;48(4):369-375. Published online April 15, 2005
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Purpose : Many inborn errors of metabolism can be completely cured with early detection and early treatment. This is why neonatal screening on inborn errors of metabolism is implemented worldwide. In this study, a cost-benefit analysis was performed on the neonatal screening of phenylketonuria and congenital hypothyroidism in Korea.
Methods : This study included 2,908,231 neonates who took the neonatal screening... |
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- Trend of Obesity in School Age Children in Seoul Over the Past 23 Years
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Young Shin Park, Dong Hwan Lee, Joong-Myung Choi, Yun Ju Kang, Chong Hee Kim
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Clin Exp Pediatr. 2004;47(3):247-257. Published online March 15, 2004
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Purpose : The aim of this study was to evaluate the change in prevalence and the epidemiology of obesity in school age children of Seoul, Korea during the last 23 years with coherency and under the same standards.
Methods : We used the new 1998 standard weight for height to calculate obesity on the personal data from five years and produced... |
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- Galactosemia Detected by Neonatal Screening Test
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Il Sung Park, Hye Jung Cho, Dong Hwan Lee, Jung Hwan Song
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Clin Exp Pediatr. 2003;46(5):440-446. Published online May 15, 2003
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Purpose : The genetic disturbance of galactosemia is expressed as a cellular deficiency of either galactose-1-phosphate uridyltransferase(GALT) or galactokinase(GALK) or UDP galactose 4-epimerase(GALE). To find-out the pattern of galactosemia in Korea, we retrospectively analyzed cases of galactosemia detected by neonatal screening program.
Methods : We analyzed medical records of patients who visited Soonchunhyang University Hospital at age of 1... |
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- Case Report
- A Case of Keratitis, Ichthyosis and Deafness(KID) Syndrome
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Lan Kim, Dong Hwan Lee
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Clin Exp Pediatr. 2003;46(11):1135-1138. Published online November 15, 2003
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KID syndrome was named after the initials of the major three symptoms of the disease; keratitis, ichthyosis, and deafness. The syndrome was first introduced by Dr. Burns in 1915 who described one of his patients with those symptoms. In 1981, Dr. Skinner and his colleagues reported 17 patients who had keratitis, ichthyosis, and deafness. They also called the disease KID... |
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- Two Cases of HHH Syndrome in Siblings
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Min Ho Hwang, Bo Sun Kim, Dong Hwan Lee
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Clin Exp Pediatr. 2001;44(10):1206-1210. Published online October 15, 2001
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Hyperornithinemia-hyperammonemia-homocitrullinuria(HHH) syndrome is a rare autosomal recessive disorder caused by a defect in the urea cycle. Protein intolerance, mental retardation, seizure, ataxia, and stupor are characteristic symptoms. Patients showing these symptoms may also present symptoms of acute hepatic disease at the same time. When fed with a high protein diet, they may refuse to eat, vomit, become lethargic, or go... |
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- Isovaleric Acidemia in Siblings Diagnosed by Organic Acid Analysis
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Kyung Soo Cheon, Dong Hwan Lee
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Clin Exp Pediatr. 2000;43(6):828-831. Published online June 15, 2000
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Isovaleric acidemia is an inborn error in metabolism due to a defect in isovaleryl-CoA dehydrogenase. Accumulation of serum isovaleric acid causes poor feeding, vomiting, lethargy, hypothermia, convulsion, mental retardation, etc. It is inherited as an autosomal recessive trait. Since the first reports of isovaleric acidemia by Tanaka et al in 1966, more than 60 cases have been reported. There are... |
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- Gastroesophageal Reflux Disease in Children with Chronic Cough
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Pan Joo Lim, Jae Ock Park, Dong Hwan Lee, Sang Mann Shin, Dong Won Kim
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Clin Exp Pediatr. 1998;41(9):1234-1242. Published online September 15, 1998
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Purpose : We investigated the incidence of gastroesophageal reflux disease(GERD) by 24-hour esophageal pH monitoring in patients who had chronic cough for more than 3 weeks.
Methods : From January 1995 to August 1996, 33 patients with chronic cough which had lasted for more than 3 weeks were enrolled in the 24-hour esophageal pH monitoring. The result was interpreted with the... |
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- Case Report
- A Case of Congenital Intestinal Lymphangiectasia
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Pan Joo Lim, Jae Ock Park, Dong Hwan Lee, Sang Mann Shin, Dong Won Ki
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Clin Exp Pediatr. 1998;41(9):1293-1298. Published online September 15, 1998
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Intestinal lymphangiectasia is a primary or secondary disorder of lymphatics which is associated with protein-losing enteropathy, hypoalbuminemia, edema, abdominal distension and growth failure. The patients with this disease lose albumin, immunoglobulins, and lymphocytes through the bowel. We have experienced one case of intestinal lymphangiectasia in 8 month-old boy, whose chief complaint was abdominal distension and watery diarrhea. He had hypoalbuminemia(1.7gm/dl).... |
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- Original Article
- Conversion Rates of Tuberculin Test according to BCG Vaccination Methods
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Woo Sung Kim, Chang Hwi Kim, Dong Hwan Lee, Sang Mann Shin
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Clin Exp Pediatr. 1997;40(4):489-496. Published online April 15, 1997
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Purpose : Tuberculosis, a major public health problem, is an important cause of childhood morbidity and mortality in developing countries. To decline the tuberculosis morbidity rate, active BCG vaccination is performed worldwide. Recently percutaneous multiple puncture technique of BCG vaccination was introduced and used because of side effects of intradermal BCG vaccination such as scar, local ulceration, regional suppurative lymphadenitis.... |
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- Serum Vitamin A Leveland Immunization Status in Serologically Confirmed Measles Patients
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Kyung Hwa Park, Seung Hee Choe, Chang Hwi Kim, Dong Hwan Lee, Sang Mann Shin, Sang Jhoo Lee
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Clin Exp Pediatr. 1996;39(2):187-194. Published online February 15, 1996
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Purpose : To know the relationship between serum vitamin A level and clinical symptoms in measles patients and to re-evaluate the measles vaccination schedule, we performed this study.
Methods : From Jan. to Jun. 1994, we checked serum vitamin A levels and compared with
clinical symptoms, laboratory findings, complications and vaccination status in 153 patients with positive measles IgM by ELISA.
Results :... |
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- The Influence of the Use of Iodine during Perinatal Period on the Screening Test for Congenital Hypothyroidism
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Gyu Bum Cho, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1996;39(2):195-206. Published online February 15, 1996
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Purpose : This study was performed to detect the diseases of congenital hypothyroidism by the neonatal mass screening test early and to demonstrate the possible role of topical iodinated antiseptics(povidone-iodine, PVP-Ⅰ) on transient hyperthyrotropinemia in newborn infants.
Methods : We performed neonatal screening tests for inborn errors of metabolism since 1985 by Guthrie test for PKU, maple syrup urine disease, histidinemia,... |
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- Upper Limit of Normal Value for Antistreptolysin O Titer of Healthy Children in Seoul
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Sung Ho Cha, Yong Mook Choi, Sei Won Yang, Dong Hwan Lee, Chong Guk Lee, Chang Ho Hong
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Clin Exp Pediatr. 1995;38(8):1061-1068. Published online August 15, 1995
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Purpose : We have found somewhat high titer of antistreptolysin O (ASO) accidentally when we had delineated normal carrier rate of beta hemolytic streptococci in rural area of Kangwon Province in 1991(1). We would like to know upper limit of normal value of ASO and re-valuated results which might be changed with different geographic areas, age, and prevalent rate... |
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- Case Report
- A Case of Congenital Lipoid Adrenal Hyperplasia
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Hae Kyung Lee, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1995;38(4):567-573. Published online April 15, 1995
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Congenital lipoid adrenal hyperplasia is the rarest type among salt losing types of congenital adrenal hyperplasia. The defect of this disorder is in the cholesterol side chain cleavage enzyme(P450SCC)which converts cholesterol to pregnenolone.
We experienced a case of 20,22 desmolse deficiency in a 21-day old phenotypically female who was admitted to our hospital due to lethargy and dark skin pigmentation. The... |
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- A Case of Sjören-Larsson Syndrome
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Kil Joon Lee, Jong Bock Kim, Dong Hwan Lee, Sang Man Shin, Sang Jhoo Lee
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Clin Exp Pediatr. 1994;37(12):1757-1761. Published online December 15, 1994
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Sjören-Larsson Syndrome is a rare disorder chracterized by congenital icthyosis, spastic diplegia or tetraplegia and mental retardation. The inheritance is autosomal recessive, due to deficiency of alcohol dehydrogenase activity of fatty acid matabolism.
We have experienced a case of Sjören-Larsson Syndrome in a 16 month-old male children who have dried thick skin, developmental delay, and spastic diplegia.
He was much improved clinically... |
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- A Case of Laryngeal Cleft
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Yong Sik Min, Hye Kyu, Jun Soo Park, Dong Hwan Lee, Sang Jhoo Lee, Hyun Sook Hong
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Clin Exp Pediatr. 1993;36(7):1016-1024. Published online July 15, 1993
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Laryngotracheoesophageal cleft is a rare congenital anomaly characterized by a midline defect of variable length between the posterior larynx and trachea and the anterior wall of the esophagus which was first reported by Richter in 1792.
The male, birth weight 2780 gm, was born our hospital. After birth the infant breathed spontaneously, cried immediately but weak and did well initially but... |
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- A Case of Syndrome Associated with Colonic Atresia
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Si Whan Koh, Joon Soo Park, Kyung Hwan Oh, Dong Hwan Lee, Sang Jhoo Lee, Chul Moon
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Clin Exp Pediatr. 1993;36(7):1030-1033. Published online July 15, 1993
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The association of colonic atresia in patients with Down syndrome is a rare anomaly. The incidence of congenital atresia of the gastrointestinal tract has been estimated to be about one in 1500 births. Colonic atresia is rarer still, and is throut to comprise about 5% to 10% of this group. This intestinal atresia occurs in about 30% to 50% of... |
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- Original Article
- Pterin & DHPR Measurement and DNA Analysis in Korean PKU Patients
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Chol Hee Chong, Hye Yong Lee, Dong Hwan Lee, Sang Jhoo Lee, Ki Weon Cha, Jeong Bin Yim, Yoshiyuki Okano
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Clin Exp Pediatr. 1993;36(12):1681-1690. Published online December 15, 1993
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Phenylketonuria in metabolic disorder that results from a deficiency of the hepatic phenylalanine hydroxylase. But among patients with hyperphenylalaninemia, the defect resides in one of the enzymes necessary for production or recycling of tetrahydrobiopterin (BH4). The reduction of BH4 affects not only phenylalanine metabolism but also formation of the tyrosine related neurotransmitter, dopamin and tryptophan related neurotransmitter, serotonin.
Administration of L-dopa... |
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- Case Report
- A Case of Neonatal Hypothyroidism due to Maternal TSH-Binding Inhibitor Immunoglobulin
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Myung Lye Kim, Rhie Choi, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1992;35(6):804-808. Published online June 15, 1992
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Neonatal screening for congenital hypothroidism is important because of the possibility that mental retardation may be avoided if treatment started early.
A 1 day old patient was admitted to our department of Pediatrics for congenital hypothyroidism screening. The mother was 33 years old and had been on thyroid replacement therapy since 32 years of age. During the pregnancy she was euthyroid... |
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- Original Article
- A Clinical Study in Phenylketonuria
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Hye Kyeong Nam, Jin Seop Shim, Dong Hwan Lee, Sang Jhoo Lee, Ki Weon Cha, Jeong Bin Yim
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Clin Exp Pediatr. 1992;35(1):69-79. Published online January 15, 1992
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Thirteen cases of phenylketonuria who were diagnosed at department of pediatrics, Soonchunhyang University Hospital, and four cases at other hospitals and other countries from July, 1984 to April, 1991 were reviewed and analyzed.
The results were as follow: 1) All 17 cases were between the age of 3 days and 19 years, and the male to female ratio was 1.43:1. 2)... |
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- Two cases of cyclopia in twin.
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Joon Soo Park, Si Hwan Kho, Dong Hwan Lee, Sang Jhoo Lee, So Young Jin
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Clin Exp Pediatr. 1991;34(5):700-706. Published online May 31, 1991
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A Cyclopia in which the elements of the two eyes are completely or partially fused to form an
apparently single eye in the middle of the forehead, is part of an anomaly involving not only the eyes
themselves but also the anterior part of the brain and the mesodermal structures in the midline.
We have experienced two cases of Cyclopia in twin.
The autopsy... |
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- A case of Mosaic trisomy 8.
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Hye Kyung Nam, Dong A Lee, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1991;34(4):553-557. Published online April 30, 1991
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Cardinal clinical features of trisomy 8 are as follow: Absent patellae; mental retardation; facies
notable or its anteverted nose, long philtrum, micrognathia and malformed ears; flexion deformities
of the fingers or toes, deep plantar V-shaped cleft between the first and third interdigital web of foot,
“pH capitonne”. More than 35 patients have been identified as having trisomy 8.
The authors experienced a patient of... |
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- The incidence of complications in severely obese children.
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Dong Hwan Lee, Chong Guk Lee, Chul Lee, Yong Seung Hwang, Sung Ho Cha, Yong Choi
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Clin Exp Pediatr. 1991;34(4):445-453. Published online April 30, 1991
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The measurement of body weight, height and blood pressure, urine sugar, oral glucose tolerance
test, S-GOT, S-GPT, cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol tests were made
in 324 severely obese elementary, middle and high school students (218 boys and 106 girls) to know the
incidence of complication in these children. .
The results were as follow:
1) S-GOT or S-GPT were increased abnormally in 38.3% and fatty livers were... |
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- Two cases of islet cell hyperplasia with nesidioblastosis.
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Myeong Ku Cho, Kyeong Bae Park, Gyu Bum Cho, Dong Hwan Lee, Sang Jhoo Lee, D.H Lee
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Clin Exp Pediatr. 1991;34(2):273-280. Published online February 28, 1991
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Hypoglycemia due to Hyperinsulinism is associated with nesidioblastosis, islet cell hyperplasia or
adenoma.
We experienced two newborn infants suffering from recurrent attacks of hypoglycemia, they were
underwent a subtotal pancreatectomy for suspected islet cell dysmaturation syndrome. No tumor was
found, but histology revealed islet cell hyperplasia and nesidioblastosis.
After surgery one case who was treated with diazoxide, had persistent hypoglycemia but the other
showed normal glucose... |
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- Two cases of meconium peritonitis.
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Hye Kyung Nam, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1991;34(2):256-260. Published online February 28, 1991
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Meconium peritonitis is a non-bacterial foreign body and chemical peritonitis occurring during
intrauterine or early neonatal life as the result of an abnormal communicatiion between the bowel
contents and the peritonesal cavity.
We experienced two cases of meconium peritonitis, diagnosed in according to the clinical and
radiologic features, in two female neonates who had the chief complaint of vomiting and abdominal
distention. A brief review... |
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- Body part identification in 1-to 5-year-old children.
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Rhie Choi, Ju Seok Maeng, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1991;34(12):1647-1654. Published online December 31, 1991
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Until recently, minimal information on the development of body part identification in young
children has been available although several developmental assessments include items that involve
pointing to or naming body part.
The purpose of this study was to examine the sequence in which body parts are learned and can be
identified by very young children.
The 360 children who 1-to 5-year-old were tested during the... |
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- Clinical and statistical observation for very low birth weight infants.
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Sung Shin Park, Ji Hee Jung, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1991;34(12):1629-1640. Published online December 31, 1991
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We made clinical and statistical observation of 90 very low birth weight infants who were admitted
at Soonchunhyang university hospital during the 6 years period from January 1985 through December
1990.
The result obtained were as follows:
1) The incidence of very low birth weight infant during 6 years period was 0.68%, and the
mortality rate was 488/1000 very low birth weight infants.
2) There was no obvious... |
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- A case of congenital lactic acidosis.
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Suk Min Choi, Myeong Ku Cho, Dong Hwan Lee, Sang Jhoo Lee, Kikumaro Aoki, Shuichi Yamaguchi
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Clin Exp Pediatr. 1991;34(1):95-100. Published online January 31, 1991
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The congenital lactic acidosis represent a sizable group of metabolic disorders.
They are in all likelihood genetically determined, and they are clearly heterogenous. They may be
considered broadly as disorders of pyruvate metabolism in which there are two general categories:
defects in gluconeogenesis and defects in pyruvate oxidation.
We experienced a case of congenital lactic acidosis in neonate who was diagnosed by urinary
organic acid... |
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- Cystinurua in Siblings.
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Sung Ik Cho, Min Yong Oum, Jae Ock Park, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1990;33(3):351-359. Published online March 31, 1990
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We report cystinuria in siblings. Renal colic, hematuria, dysuria and stone passage were developed
in younger brother (4 year 6 month old boy). But the elder sister (6 year old girl) had no specific
symptoms nor signs.
The identification of the disease was proved by cyanide nitroprusside test and amino acid analysis
of urine.
In our patients the chromatographic amino acid patterns of urine showed... |
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- A Case of Nonimmunologic Hydrops Fetalis Associated with Down Syndrome.
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Sang Eun Lee, Meen Jai Lee, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1990;33(2):205-211. Published online February 28, 1990
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We experienced a case of nonimmunologic hydrops fetalis associated with Down syndrome.
The patient had generalized edema with severe scrotal swelling and abdominal distension.
A roentgenogram showed bilateral pleural effusion and ascites. The chromosomal study revealed
21 trisomy.
On autopsy, there were pleural fluid and ascites as well as pericardial fluid. Small ASD and
incomplete lobation of the right lung were detected.
Chromosomal abnormalities should always... |
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- Clinical Evaluation in Lipoid Pneumonia.
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Myeong Ku Cho, Suk Min Choi, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1990;33(12):1656-1661. Published online December 31, 1990
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Seven cases of lipoid pneumonia in infant who were admitted to department of pediatrics, Soon
Chun Hyang University Hospital from July 1988 to March 1990 were reviewed and analysed.
The results were as follows:
1) All cases were taken shark liver oil (squalene®) forcefully in supine position
2) Out of 7, all cases were between the age of 3 months and 6 months, and the male... |
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- A Study on Lighting in school.
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Kyung Hwan Oh, Woo Ryung Lee, Sang Cheol Park, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1990;33(12):1623-1630. Published online December 31, 1990
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The students had to spend their most of times in school. It was supposed that the lighting of
classrooms greatly affected the growth and development and visual acuity of students.
The illuminance was measured in 12 classrooms of Chun An city (primary, middle and high school)
from July to September, 1989.
To evaluate the present status and problems of lighting in classrooms, we analyzed... |
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- Analysis of Asymptomatic Proteinuria in School Children.
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Chong Guk Lee, Tae Sub Shim, Dong Hwan Lee, Yong Soo Yun, Chang Jun Ko, Sa Jun Chung, Hyun Soon Lee, Sung Jae Suh, Pyung Nam Kim
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Clin Exp Pediatr. 1989;32(9):1187-1194. Published online September 30, 1989
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Uriary mass screening program for the detection of proteinuria had been performed for a school-
age population in the city of Seoul since 1981. Annually, about half million students, who comprised
3 different age group, corresponding to the averages of 11，14, and 17 years, had been examined. A
systematic clinical evaluation was designed for students with proteinuria identified in the mass
screening through ’87... |
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- The Precalence and Trend of Obesity in Children and Adolescents.
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Kyu Bum Cho, Soon Bok Park, Sang Chul Park, Dong Hwan Lee, Sang Jhoo Lee, Sung Jae Suh
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Clin Exp Pediatr. 1989;32(5):597-605. Published online May 31, 1989
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The pose of this study is to survey the prevalence and trend of obesity at ages 6 to 11 in Seoul
from 1984 to 1988. The number of children and adolescents comprised of 5,391 boys and 5,289 girls.
Overweight was defined as weight that exceeded the standard weight for height and sex by more than
20% (relaive weight > 120%).
The result was as... |
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- A Case of Type A Niemann-Pick Disease.
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Young Bong Moon, Yang Bin Im, Dong Hwan Lee, Sang Jhoo Lee, In Sook Kim, Tae Jung Kwon, Dong Wha Lee
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Clin Exp Pediatr. 1989;32(3):402-411. Published online March 31, 1989
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We experienced a case of type A Niemann-Pick disease in 31 month-old female infant. She showed
dyspnea, marked hepatosplenomegaly and developmental retardation. Fundoscopic examination
revealed cherry red spots in both macula. Autopsy finding revealed that Iiver, spleen, lung, kidney,
bone marrow, lymph node and brain were involved. Especially multiple ischemic necrosis were found
on cerebral and cerebellar white matter. Generalized muscular atrophy and reticular... |
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- A Case of Neonatal Short Bowel Syndrome.
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Gill Hyoun Kim, In Chul Yoo, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1989;32(1):81-86. Published online January 31, 1989
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We experienced a case of neonatal short bowel syndrome due to multiple jejuno-ileal atresia with
microcolon.
On the 1st day of her life, there were symptoms of vomiting and abdominal distension. The
radiological study show multiple dilated intestinalloops and malrotation. On the 4th day of her life,
the extensive enterectomy was done. The remaining small bowel consisted of 30 cm of proximal
jejunum and distal... |
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- A Case of Fetal Alcohol Syndrome.
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Kee Don Hong, In Chul Yoo, Hung Sub Choi, Dong Hwan Lee, Snag Jhoo Lee
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Clin Exp Pediatr. 1988;31(3):375-380. Published online March 31, 1988
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We experienced a case of fetal alcohol syndrome in 9 day old male neonate who delivered at term.
On maternal history, his mother had been drunk as much as 64 to 96 cc of alcohol everyday during
first trimester and third trimester. The baby had a small for gestational age, microcephaly, bilateral
micro-ophthalmia, short palpebral fissure, shallow philtrum, posterior rotation of helix, vocal... |
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- Pancreatic ISlet-cell Adenoma in a Neonate.
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Kyu Bum Cho, Yang Bin Im, Dong Hwan Lee, Sang Jhoo Lee, Tae Jeong Kwon, Dong Hwa Lee
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Clin Exp Pediatr. 1988;31(12):1650-1656. Published online December 31, 1988
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Islet cell adenoma is a rare cause of severe neonatal hypoglycemia. A newborn infant with severe
symptomatic hypoglycemia had persistent hypoglycemia in spite of therapy with parenteral glucose
solution.
Islet-cell adenoma of mixed islet-acinar type was found when subtotal pancreatectomy was
performed at 42 days of age. Following surgery she had a transient hyperglycemia and required isulin
for 40 days. She has remained normoglycemic but... |
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- Case Report
- A case of Pierre-Robin Syndrome.
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Soon Ja Han, yeongok bang, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1982;25(4):419-422. Published online April 30, 1982
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Micrognathia, cleft palate and glossoptosis, a combination of anomalies known as Pierre Robin syndrome, causes severe respiratory and alimentary difficulties in affected infants. With appropriate care and treatment, mental development can be made normal. But about 10~25% of children become retarded. We have experienced above case in a female infant, aged 6 months. She was acmitted on account of respiratory... |
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- A Case of Staphylococcal Scalded Skin Syndrome.
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Jung Sook Moon, Soo Ok Lee, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1981;24(2):169-172. Published online February 15, 1981
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The authors experienced a case of staphylococcal scalded skin syndrome in 6 month old male infant and reported with brief review of literatures. His chief complaints on admission were fever, vomiting, and watery diarrhea for one day. On the fourth hospitalization day, generalized erythema was developed which was followed by generalized skin exfoliation and methicillin therapy was started. On the... |
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- A Case Report of Congenital Ileal Atresia with Microcolon.
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Eun Kim, Hye Young Hwang, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1979;22(9):809-813. Published online September 15, 1979
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This is a case report of the congenital ileal atresia with disuse microcolon. The patient was a 3 day-old male newborn infant who was admitted in department of pediatrics Soon Chun Hyang Hospital with complaints of persistant vomitings, no meconium passage, and jaundice from a few hours after birth. The diagnosis was established by characteristic clinical features and barium enuma... |
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- Original Article
- Standards for the Area and Volume of the Sella Turcica in Korean Children.
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Dong Hwan Lee
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Clin Exp Pediatr. 1979;22(2):81-93. Published online February 15, 1979
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The sella turcica is often the key to intracranial diseases and some endocrine disorders. It is significanly enlarged in hypothyroidism, pituitary tumors, some types of increased intracranial pressure and decreased in size in hypopituitarism. Estimation of the sellar size by naked eye is not scientific and moreover very difficult, especially in the borderline sella, an everyday problem of radiologist and... |
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- Case Report
- Two Cases of Kasabach-Merritt Syndrome.
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Hye Yong Hwang, Eun Kim, Jae Ock Park, Dong Hwan Lee, Sang Jhoo Lee
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Clin Exp Pediatr. 1979;22(12):1067-1073. Published online December 15, 1979
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Kasabach-Merritt syndrome is rare disorder which consists of hemangioma and thromobocytopenia occurring in infatns. Two cases of giant hemanioma with thrombocytopenia and anemia are reported with review of literures. It is postulated that the abnormalities resulted from intravascular coagulation within the hemangioma. Those patients were managed with prednisolone administration, blood transfusion and compression with the elastic bandage over the hemangioma.... |
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- Original Article
- Clinical Eeffects of Ferrocholinate in the Iron Deficiency Anemia of Children.
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Dong Hwan Lee, Jong Gu Yoon, Kwang Wook Ko
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Clin Exp Pediatr. 1978;21(9):568-572. Published online September 30, 1978
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Ferrocholinate, choline citrate iron salt is a new chelate iron which is synthesized by reacting ferric hydroxide with choline dihydrogen citrate. Ferrocholinate is used in the prevention and treatment of microcytic, hypochromic anemias due to iron deficiency. Ferrocholinate does not release high concentrations of free ionic iron in the gastrointestinal tract and clinical reports, although limited, seem to indicate that... |
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- Standards for Medial Canthal, Lateral Canthal and Interpupillary Distances of Korean Children
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Dong Hwan Lee
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Clin Exp Pediatr. 1976;19(1):40-47. Published online January 31, 1976
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Because of racial differences in the shape and proportions of the skull, orbital distance and amount of the soft tissues about the eyes, patients should be compared with their own racial norms of interpupillary and canthal distances in diagnosis of hypertelorism or hypotelorism. However normal vaules have not been published yet in Korea. Measurements of 1535 Korean children (Male 756；... |
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